The University of Michigan Health and Retirement Study (HRS) is a longitudinal panel study that surveys a representative sample of more than 26,000 Americans over the age of 50 every two years. The HRS explores the changes in labor force participation and the health transitions that individuals undergo toward the end of their work lives and in the years that follow, collecting information about income,...

The Women's Health Initiative (WHI) is a longitudinal national health study sponsored by the National Heart, Lung, and Blood Institute (NHLBI) that focuses on strategies for preventing heart disease, breast cancer, colorectal cancer, and osteoporotic fractures in postmenopausal women in the United States. The study includes data from 161,808 women aged 50-79 years old at the time of enrollment. Available...

The Atherosclerosis Risk in Communities (ARIC) Study is a prospective longitudinal epidemiological study conducted in four U.S. communities in North Carolina, Massachusetts, Maryland, and Minnesota. ARIC is designed to investigate the causes of atherosclerosis and its clinical outcomes, and variations in cardiovascular risk factors, medical care, and disease by race, gender, location, and date. ARIC...

The Jackson Heart Study (JHS) is a population-based longitudinal study based in Jackson, Mississippi that investigates risk factors for cardiovascular disease among African Americans. It is a collaborative research project by the University of Mississippi Medical Center, Jackson State University, and Tougaloo College. The primary objective is to investigate environmental and genetic factors associated...

The Benchmark for Automatic Glottis Segmentation (BAGLS) dataset contains 59,250 high-speed laryngeal videoendoscopy frames and individually annotated segmentation masks obtained from anonymized recordings of 640 consenting subjects across multiple hospitals in Europe and the United States. Participating institutions were Boston University; Louisiana State University; New York University; Sint-Augustinus...

The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial was a large randomized controlled trial that assessed whether certain screening practices decreased deaths from prostate, lung, colorectal and ovarian cancer. Approximately 155,000 men and women aged 55 to 74 years old were enrolled from 10 screening centers across the United States between November 1993 and July 2001. Participants...

With an emphasis on reaching historically underrepresented populations, the All of Us Research Program recruits adults aged 18 and above across the United States to share their health data to enable new insights into human health and research on precision medicine. Participants contribute electronic health records (EHR), survey responses, biospecimens, wearable devices (biometrics), and physical measurements....

Clinical data was extracted from electronic health records from patients treated for hip fractures by the Department of Orthopedic Surgery at NYU Langone Health between October 2014 and February 2020. A total of 1,590 patients aged 55 and older were included in the retrospective review with complete records for patient's sex; body mass index; comorbidities as measured with the Charlson Comorbidity...

The Alzheimer’s Disease Neuroimaging Initiative (ADNI) began in 2004 as longitudinal multicenter study to identify clinical, imaging, genetic, and biochemical biomarkers for the detection and tracking of Alzheimer’s disease (AD). Participants are recruited from and followed at 59 research sites in the United States and Canada. ADNI1 enrolled 400 subjects who were diagnosed with mild cognitive impairment...

The National Alzheimer’s Coordinating Center (NACC) was created in 1999 to facilitate research with data collected from Alzheimer's Disease Research Centers (ADRCs) across the United States. NACC oversees data collection and sharing for a number of datasets. The Uniform Data Set (UDS) contains longitudinal and standardized data collected from ADRCs since 2005. ADRC enrollment protocols vary and...